CREST [Society 5.0 System Software]

Anonymous healthcare cohort with the guarantee of data privacy and utility

Project Overview

This project is the 2021 JST Strategic Creative Research Promotion Project( CREST) Research area, "Creation of basic software for Society 5.0 by fusing basic theory and system basic technology", Toshio Okabe Director) This is the research project "Anonymous healthcare cohort with the guarantee of data privacy and utility".
We aim to establish next-generation anonymously processed data that is theoretically secure against the threat of re-identification and gives a statistical evaluation of errors that occur during processing. Integrated health diagnosis data, healthcare data, and health insurance clain data are used for lifestyle-related diseases. With a mathematical model that predicts the morbidity of injuries and illnesses, it is possible to improve the lives of insured persons, create health strategies in the government, and develop pharmaceutical products at an early stage.

Groups

Group name Principal or Principal
Name of collaborator 		Principal or Principal
Collaborator's institution / department / job title 		Research subject
Kikuchi Group Hiroaki Kikuchi Meiji University, Faculty of Comprehensive Mathematics, Professor Research Supervision
Differential Privacy Anonymization technology using synthetic medical data
Kanamori Group Sachiko Kanamori National Institute of Information and Communications Technology
Cyber Security Research Institute / Director 		Privacy Enhaced Data Analysis
Arai Group Hiromi Arai RIKEN/ AI Safety and Reliability Unit
Unit Leader 		To develop explanation methods for consent
Mori Group Yukiko Mori Kyoto University Hospital, Lecturer Usefulness of anonymously medical data
Nojima Group Ryo Nojima Ritsumeikan University, Faculty of Informatics, Professor Application of security index of anonymization to machine learning

Research Group

Principal Investigator Group Kikuchi Group

Name of Principal Investigator Affiliation, department Position
Hiroaki Kikuchi Meiji University, Faculty of Comprehensive Mathematics Professor
Names of research participants Affiliation, department (omitted if same as above) Position
Andres Hernandez-Matamoros Postdoctoral Fellow
Satoshi Ito Faculty of Bussines and Commerce, Aichi Gakuin University Lecturer
Koji Chida Faculty of Informatics, Gunma University Associate Professor
Koki Hamada Nippon Telegraph and Telephone Corporation,NTT Social Informatics Laboratories Associate Special Researcher
Masanobu Kii Employee
Hideo Yasunaga The University of Tokyo, Graduate School of Medicine, Department of Public Health Medicine Professor

Research implementation items and outline

Research subject

Differential Private process for anonymization

Research implementation items

As the principal investigator, we supervise all research groups and we are in charge of three tasks.
Challenge 2. Anonymization benchmark using synthetic medical data
Issue 3. Proposal of processing method that guarantees theoretical security against re-identification by differential privacy
Problem 4. Establishment of utility measure that guarantees error range using moment generating function

Collaborative Research Group (1) Kanamori Group

Name of Principal Investigator Affiliation, department Position
Sachiko Kanamori National Institute of Information and Communications Technology Cyber ​​Security Research Institute, Security Infrastructure Laboratory Director
Names of research participants Affiliation, department (omitted if same as above) Position
Le Trieu Phong Senior Research
Lihua Wang Senior Research
Hajime Ono Researcher

Research implementation items and outline

Research subject

Privacy-protected data analysis method

Research implementation items

Proposal of processing method that guarantees theoretical safety against re-identification by differential privacy

Collaborative Research Group (2) Arai Group

Name of Principal Investigator Affiliation, department Position
Hiromi Arai RIKEN Center for Advanced Intelligence Research Unit leader
Names of research participants Affiliation, department (omitted if same as above) Position
Tetsushi Oki Department of Information Science, Faculty of Informatics, Shizuoka University Associate Professor
Tadashi Mima Keio University Graduate School of Media and Governance Project Professor
Sakamoto Taka DataSign Inc. Product Managertd>

Research implementation items and outline

Research subject

Development of a sound explanation method for obtaining consent

Research implementation items

(1) Research on explanation of personal data usage
(2) Development of information presentation method to explain the use of personal data

Collaborative Research Group (4) Mori Group

Name of Principal Investigator Affiliation, department Position
Yukiko Mori Kyoto University Hospital, Medical Information Planning Department Lecturer
Names of research participants Affiliation, department (omitted if same as above) Position
Tomohiro Kuroda Kyoto University Hospital Medical Information Planning Department Professor
Kenichi Saito Specific Assistant Professor
Toshiyuki Inagaki Life Data Initiative, General Incorporated Association Secretary General
Jun Suzumoto Department of Medical Informatics, Graduate School of Medicine, Kyoto University Doctoral Program University Students
Keita Fukuyama Medical Information Planning Department Teacher Assistant
Roberto Espinoza Chamorro Graduate School of Informatics, Kyoto University Social Informatics Course, Medical Informatics Ph.D. Student

Collaborative Research Group (5)Nojima Group

Names of research participants Affiliation, department (omitted if same as above) Position
Ryo Nojima Ritsumeikan University, Faculty of Informatics Professor

Research implementation items and outline

Research subject

Quality evaluation of anonymously processed information

Research implementation items

(1) Verification using actual medical information of anonymous processing by differential privacy
(2) Verification of analysis reproducibility using anonymously processed information

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